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|Variant||ARID1A - MAST2|
|Protein Effect||gain of function - predicted|
|Gene Variant Descriptions||ARID1A-MAST2 results from the fusion of ARID1A and MAST2 and leads to increased cell proliferation in culture (PMID: 22101766), and is therefore predicted to result in a gain of function. ARID1A-MAST2 has been identified in breast carcinoma (PMID: 22101766).|
|Associated Drug Resistance|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|
|ARID1A - MAST2||gain of function - predicted|