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Gene | MPL |
Variant | mutant |
Impact List | unknown |
Protein Effect | unknown |
Gene Variant Descriptions | MPL mutant indicates an unspecified mutation in the MPL gene. |
Associated Drug Resistance |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
MPL mutant | essential thrombocythemia | not applicable | N/A | Guideline | Diagnostic | MPL mutations aid in the diagnosis of essential thrombocythemia (NCCN.org). | detail... |
MPL mutant | myelofibrosis | not applicable | N/A | Guideline | Diagnostic | MPL mutations aid in the diagnosis of primary myelofibrosis (NCCN.org). | detail... |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
MPL mutant | unknown |