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Gene FGFR3
Variant L794fs
Impact List frameshift
Protein Effect unknown
Gene Variant Descriptions FGFR3 L794fs results in a change in the amino acid sequence of the Fgfr3 protein beginning at aa 794 of 806, likely resulting in a premature truncation of the functional protein (UniProt.org). L794fs has not been characterized in the scientific literature and therefore, its effect on Fgfr3 protein function is unknown (PubMed, Mar 2023).
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 L794fs

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Transcript NM_000142.4
gDNA chr4:g.(1807220_1807221)
cDNA c.(2380_2379)
Protein p.L794fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000142.4 chr4:g.(1807220_1807221) c.(2380_2379) p.L794fs RefSeq GRCh38/hg38
XM_006713873 chr4:g.(1807217_1807218) c.(2380_2379) p.L794fs RefSeq GRCh38/hg38
NM_000142 chr4:g.(1807220_1807221) c.(2380_2379) p.L794fs RefSeq GRCh38/hg38
XM_006713873.1 chr4:g.(1807217_1807218) c.(2380_2379) p.L794fs RefSeq GRCh38/hg38
XM_006713872 chr4:g.(1807217_1807218) c.(2380_2379) p.L794fs RefSeq GRCh38/hg38
NM_001354809.1 chr4:g.(1807217_1807218) c.(2380_2379) p.L794fs RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References