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Gene | HRAS |
Variant | S106W |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS S106W does not lie within any known functional domains of the Hras protein (UniProt.org). S106W has not been characterized and therefore, its effect on Hras protein function is unknown (PubMed, Nov 2020). |
Associated Drug Resistance |
Transcript | NM_005343.3 |
gDNA | chr11:g.533586G>C |
cDNA | c.317C>G |
Protein | p.S106W |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_005343.3 | chr11:g.533586G>C | c.317C>G | p.S106W | RefSeq | GRCh38/hg38 |
NM_176795.4 | chr11:g.533586G>C | c.317C>G | p.S106W | RefSeq | GRCh38/hg38 |
NM_001130442.2 | chr11:g.533586G>C | c.317C>G | p.S106W | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
HRAS S106W | unknown |