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Gene | KDR |
Variant | I1077L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | KDR (VEGFR2) I1077L lies within the protein kinase domain of the Kdr (Vegfr2) protein (UniProt.org). I1077L has not been characterized in the scientific literature and therefore, its effect on Kdr (Vegfr2) protein function is unknown (PubMed, Feb 2021). |
Associated Drug Resistance |
Transcript | NM_002253.3 |
gDNA | chr4:g.55089766T>G |
cDNA | c.3229A>C |
Protein | p.I1077L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002253 | chr4:g.55089766T>G | c.3229A>C | p.I1077L | RefSeq | GRCh38/hg38 |
NM_002253.3 | chr4:g.55089766T>G | c.3229A>C | p.I1077L | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
KDR I1077L | unknown |