Gene Variant Detail

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Gene FOXL2
Variant T76M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FOXL2 T76M lies within the fork-head DNA binding region of the Foxl2 protein (UniProt.org). T76M has been identified in sequencing studies (PMID: 23525077), but has not been biochemically characterized and therefore, its effect on Foxl2 protein function is unknown (PubMed, May 2020).
Associated Drug Resistance

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Transcript NM_023067
gDNA chr3:g.138946496G>A
cDNA c.227C>T
Protein p.T76M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_023067 chr3:g.138946496G>A c.227C>T p.T76M RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Protein Effect Treatment Approaches
FOXL2 T76M unknown