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|Gene Variant Descriptions||ABL1 L302H lies within the protein kinase domain of the Abl1 protein (UniProt.org). ABL1 L302H has been associated with secondary drug resistance in the context of an ABL1 fusion (PMID: 33390067), but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Nov 2022).|
|Associated Drug Resistance||Y|
|Category Variants Paths||
ABL1 mutant ABL1 L302H
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|