Gene Variant Detail

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Gene ROS1
Variant P1020S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 P1020S lies within fibronectin type-III domain 4 of the Ros1 protein (UniProt.org). P1020S has not been characterized in the scientific literature and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2022).
Associated Drug Resistance

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Transcript NM_002944.2
gDNA chr6:g.117365120G>A
cDNA c.3058C>T
Protein p.P1020S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011536057.3 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536057 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
NM_002944.2 chr6:g.117365120G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536055.2 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536056.2 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536049.2 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
NM_002944 chr6:g.117365120G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536055 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536054.2 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536054 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536049 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536058 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536058.2 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38
XM_011536056 chr6:g.117365150G>A c.3058C>T p.P1020S RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
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  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Protein Effect Treatment Approaches
ROS1 P1020S unknown