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Gene CDKN2A
Variant V28_E33del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CDKN2A V28_E33del results in the deletion of six amino acids in ANK repeat 1 of the Cdkn2a protein from amino acids 28 to 33 (UniProt.org). V28_E33del has not been characterized in the scientific literature and therefore, its effect on Cdkn2a protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A V28_E33del

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Transcript NM_000077.5
gDNA chr9:g.21974733_21974750del18
cDNA c.83_100del18
Protein p.V28_E33delVRALLE
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001363763.2 chr9:g.21971108_21971125del18 c.82_99del18 p.T28_D33delTRPVHD RefSeq GRCh38/hg38
NM_058197.4 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33del RefSeq GRCh38/hg38
NM_058197.5 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33delVRALLE RefSeq GRCh38/hg38
NM_058195.4 chr9:g.21994233_21994250del18 c.82_99del18 p.P28_E33delPRLTGE RefSeq GRCh38/hg38
XM_011517675.3 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33delVRALLE RefSeq GRCh38/hg38
XM_047422596.1 chr9:g.21971108_21971125del18 c.82_99del18 p.T28_D33delTRPVHD RefSeq GRCh38/hg38
NM_001195132.2 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33delVRALLE RefSeq GRCh38/hg38
XM_011517676.3 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33delVRALLE RefSeq GRCh38/hg38
XM_047422597.1 chr9:g.21971108_21971125del18 c.82_99del18 p.T28_D33delTRPVHD RefSeq GRCh38/hg38
NM_001195132.1 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33del RefSeq GRCh38/hg38
NM_000077.4 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33del RefSeq GRCh38/hg38
XM_047422598.1 chr9:g.21971108_21971125del18 c.82_99del18 p.T28_D33delTRPVHD RefSeq GRCh38/hg38
XM_011517675.2 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33del RefSeq GRCh38/hg38
XM_011517676.2 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33del RefSeq GRCh38/hg38
NM_000077.5 chr9:g.21974733_21974750del18 c.83_100del18 p.V28_E33delVRALLE RefSeq GRCh38/hg38

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References