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Gene | HRAS |
Variant | G13N |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS G13N lies within the GTP nucleotide binding region of the Hras protein (UniProt.org). G13N has not been characterized in the scientific literature and therefore, its effect on Hras protein function is unknown (PubMed, Nov 2023). |
Associated Drug Resistance | |
Category Variants Paths |
HRAS mutant HRAS G13X HRAS G13N |
Transcript | NM_005343.4 |
gDNA | chr11:g.534285_534286delGGinsAA |
cDNA | c.37_38delGGinsAA |
Protein | p.G13N |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_005343.3 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
NM_005343.4 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
NM_176795.5 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
NM_001130442.3 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
NM_001130442.2 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
NM_176795.4 | chr11:g.534285_534286delGGinsAA | c.37_38delGGinsAA | p.G13N | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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