Gene Variant Detail

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Gene HRAS
Variant G13N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS G13N lies within the GTP nucleotide binding region of the Hras protein (UniProt.org). G13N has not been characterized in the scientific literature and therefore, its effect on Hras protein function is unknown (PubMed, Nov 2023).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS G13X HRAS G13N

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Transcript NM_005343.4
gDNA chr11:g.534285_534286delGGinsAA
cDNA c.37_38delGGinsAA
Protein p.G13N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001130442.3 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_176795.5 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_176795.4 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_005343.3 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38
NM_005343.4 chr11:g.534285_534286delGGinsAA c.37_38delGGinsAA p.G13N RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
HRAS G13N unknown MEK inhibitor (Pan) MEK1 Inhibitor MEK2 Inhibitor PI3K Inhibitor (Pan) PIK3CA inhibitor PIK3CB inhibitor PIK3CD inhibitor PIK3CG inhibitor RAS Inhibitor (Pan)