Gene Variant Detail

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Gene BRAF
Variant V471I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF V471I lies within the protein kinase domain of the Braf protein (UniProt.org). V471I has been identified in sequencing studies (PMID: 28188106, PMID: 23103869), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Nov 2022).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF V471I

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Transcript NM_004333.5
gDNA chr7:g.140781597C>T
cDNA c.1411G>A
Protein p.V471I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004333 chr7:g.140781597C>T c.1411G>A p.V471I RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140781597C>T c.1411G>A p.V471I RefSeq GRCh38/hg38
XM_005250045 chr7:g.140781597C>T c.1411G>A p.V471I RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140781597C>T c.1411G>A p.V471I RefSeq GRCh38/hg38

Filtering

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  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries