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Gene | CTNNB1 |
Variant | L31M |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | CTNNB1 L31M does not lie within any known functional domains of the Ctnnb1 protein (UniProt.org). L31M has not been characterized and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Mar 2022). |
Associated Drug Resistance |
Transcript | NM_001098210.1 |
gDNA | chr3:g.41224603C>A |
cDNA | c.91C>A |
Protein | p.L31M |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001098210 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_017005738 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_005264886 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
NM_001098209 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_024453356.1 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_017005738.1 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
NM_001904 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
NM_001098210.1 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_024453357.1 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_006712985 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
NM_001098209.1 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_024453358.1 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
XM_006712985.1 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
NM_001904.3 | chr3:g.41224603C>A | c.91C>A | p.L31M | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
CTNNB1 L31M | unknown |