Gene Variant Detail

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Gene ATR
Variant R1503*
Impact List nonsense
Protein Effect loss of function - predicted
Gene Variant Descriptions ATR R1503* results in a premature truncation of the Atr protein at amino acid 1503 of 2644 (UniProt.org). Due to the loss of most known functional domains (UniProt.org), R1503* is predicted to lead to a loss of Atr protein function.
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR inact mut ATR R1503*

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Transcript NM_001184.3
gDNA chr3:g.142513635G>A
cDNA c.4507C>T
Protein p.R1503*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184 chr3:g.142513635G>A c.4507C>T p.R1503* RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142513635G>A c.4507C>T p.R1503* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries