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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|KIT Y823D||Advanced Solid Tumor||sensitive||KIT Inhibitor||Motesanib Diphosphate||Preclinical - Cell culture||Actionable||In a preclinical study, Motesanib (AMG 706) inhibited KIT phosphorylation and growth of cells expressing KIT Y823D in culture (PMID: 20633291).||20633291|