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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FLT3 exon 14 ins FLT3 S652G||leukemia||predicted - resistant||Pexidartinib||Case Reports/Case Series||Actionable||In a clinical case study, a patient with FLT3-ITD positive leukemia initially responded to Pexidartinib (PLX3397), but experienced relapse after emergence of a FLT3 S652G mutation on the same allele as FLT3-ITD (PMID: 25847190).||25847190|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|