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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|STK11 D194E STK11 loss||pancreatic cancer||predicted - sensitive||Everolimus||Case Reports/Case Series||Actionable||In a clinical case study, a pancreatic cancer patient with Peutz-Jeghers syndrome harboring STK11 D194E and loss of heterozygosity of the other STK11 allele in the tumor achieved a partial response following treatment with Afinitor (everolimus), but progressed after 9 months (PMID: 21189378).||21189378|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|