Molecular Profile Detail

Profile Name APC mutant KRAS mutant KDR R961W
Gene Variant Detail

APC mutant (unknown)

KDR R961W (unknown)

KRAS mutant (unknown)

Relevant Treatment Approaches


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Molecular Profile Indication/Tumor Type Response Type Relevant Treatment Approaches Therapy Name Approval Status Evidence Type Efficacy Evidence References
APC mutant KRAS mutant KDR R961W colorectal cancer predicted - sensitive Regorafenib Case Reports/Case Series Actionable In a clinical case study, Stivarga (regorafenib) treatment resulted in durable partial response in a colorectal cancer patient harboring KDR R961W and mutations in APC and KRAS (PMID: 27004155). 27004155
Clinical Trial Phase Therapies Title Recruitment Status