Molecular Profile Detail

Profile Name ETV6-SYK
Gene Variant Detail

ETV6 ETV6 - SYK (gain of function)

Relevant Treatment Approaches


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Molecular Profile Indication/Tumor Type Response Type Relevant Treatment Approaches Therapy Name Approval Status Evidence Type Efficacy Evidence References
ETV6-SYK Advanced Solid Tumor sensitive HMPL-523 Preclinical - Cell culture Actionable In a preclinical study, HMPL-523 decreased viability of cells expressing ETV6-SYK in culture (Blood Dec 2016, 128 (22) 3970). detail...
Clinical Trial Phase Therapies Title Recruitment Status