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|Profile Name||BCOR mutant|
|Gene Variant Detail|
|Relevant Treatment Approaches|
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|BCOR mutant||kidney clear cell sarcoma||not applicable||N/A||Clinical Study||Emerging||In multiple clinical analyses, internal tandem duplications of the BCOR gene were consistently found in clear cell sarcoma of the kidney (PMID: 26098867, PMID: 26516930, PMID: 26573325, PMID: 26150234), suggesting that this may serve as a future diagnostic biomarker.||26150234 26098867 26516930 26573325|
|BCOR mutant||myelodysplastic syndrome||not applicable||N/A||Guideline||Prognostic||BCOR mutations, including those at codon N1425, are associated with a poor prognosis in patients with myelodysplastic syndrome (NCCN.org).||detail...|