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|Profile Name||RAD21 wild-type|
|Gene Variant Detail|
|Relevant Treatment Approaches|
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|RAD21 wild-type||breast cancer||not applicable||N/A||Preclinical||Emerging||In a preclinical study, siRNA inhibition of RAD21 in breast cancer cells resulted in increased sensitivity to Toposaur (etoposide) in culture, suggesting RAD21 may be a potential therapeutic target for enhanced sensitivity to chemotherapeutics (PMID: 15767545).||15767545|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|