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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ERBB2 S310F ERBB2 G660D||ampulla of Vater carcinoma||predicted - sensitive||Afatinib||Case Reports/Case Series||Actionable||In a clinical case study, Gilotrif (afatinib) treatment resulted in stable disease with slight lymph node metastasis reduction in a patient with ampulla of Vater carcinoma harboring ERBB2 S310F and G660D, but the disease eventually progressed after 4 months (PMID: 29146616).||29146616|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|