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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|BRAF V600X PTEN neg||melanoma||sensitive||Uprosertib||Preclinical - Cell culture||Actionable||In a preclinical study, lack of PTEN expression was associated with increased sensitivity to GSK2141795 in BRAF V600-mutant melanoma cell lines in culture (PMID: 24265152).||24265152|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|