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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|APC E853* APC K1555*||colorectal cancer||sensitive||TASIN-1||Preclinical - Cell line xenograft||Actionable||In a preclinical study, TASIN-1 efficiently inhibited survival of colorectal cancer cells harboring APC E853* and APC K1555* in culture and inhibited tumor growth in xenograft models (PMID: 27798265).||27798265|