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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FLT3 wild-type MERTK pos||acute myeloid leukemia||sensitive||MRX-2843||Preclinical - Cell line xenograft||Actionable||In a preclinical study, MRX-2843 inhibited Mertk signaling, resulted in growth inhibition in FLT3 wild-type acute myeloid leukemia cells in culture and in cell line xenograft models, and prolonged survival in patient-derived xenograft models (PMID: 27158668).||27158668|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|