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Profile Name | KDR D717V |
Gene Variant Detail | |
Relevant Treatment Approaches | VEGFR Inhibitor (Pan) VEGFR2 Inhibitor |
Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|---|
KDR D717V | Advanced Solid Tumor | sensitive | VEGFR2 Inhibitor | Sunitinib | Preclinical - Cell culture | Actionable | In a preclinical study, cells expressing KDR D717V were sensitive to Sutent (sunitinib) in culture (PMID: 19723655). | 19723655 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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