Molecular Profile Detail

Profile Name SF3B1 R1074H
Gene Variant Detail

SF3B1 R1074H (unknown)

Relevant Treatment Approaches

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Molecular Profile Indication/Tumor Type Response Type Relevant Treatment Approaches Therapy Name Approval Status Evidence Type Efficacy Evidence References
SF3B1 R1074H Advanced Solid Tumor resistant H3B-8800 Preclinical - Cell culture Actionable In a preclinical study, transformed cells overexpressing SF3B1 R1074H were resistant to H3B-8800 in culture (Blood 2016 128:966). detail...
Clinical Trial Phase Therapies Title Recruitment Status