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|Profile Name||STAG2 mutant|
|Gene Variant Detail|
|Relevant Treatment Approaches|
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|STAG2 mutant||myelodysplastic syndrome||not applicable||N/A||Guideline||Prognostic||STAG2 mutations are associated with a poor prognosis in patients with myelodysplastic syndrome (NCCN.org).||detail...|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT03613532||Phase I||Busulfan + Fludarabine + Venetoclax||Venetoclax Added to Fludarabine + Busulfan Prior to Transplant for AML, MDS, and MDS/MPN||Recruiting|
|NCT03974217||Phase I||Talazoparib||Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts||Recruiting|