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|Profile Name||U2AF1 Q157X|
|Gene Variant Detail|
|Relevant Treatment Approaches|
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|U2AF1 Q157X||myelofibrosis||not applicable||N/A||Guideline||Prognostic||U2AF1 Q157 mutations are associated with inferior overall survival compared to U2AF1 S34 mutations or wild-type U2AF1 in patients with primary myelofibrosis (NCCN.org).||detail...|
|U2AF1 Q157X||myelodysplastic syndrome||not applicable||N/A||Guideline||Prognostic||U2AF1 Q157X is associated with a poor prognosis in patients with myelodysplastic syndrome (NCCN.org).||detail...|