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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ETV6 - NTRK1||Advanced Solid Tumor||sensitive||DS6051b||Preclinical - Cell culture||Actionable||In a preclinical study, transformed cells expressing ETV6-NTRK1 were sensitive to treatment with DS6051b in culture, demonstrating cell growth inhibition (PMID: 31399568).||31399568|
|ETV6 - NTRK1||Advanced Solid Tumor||predicted - sensitive||Entrectinib||Preclinical - Cell culture||Actionable||In a preclinical study, transformed cells expressing ETV6-NTRK1 were sensitive to Rozlytrek (entrectinib) as demonstrated by reduced proliferation relative to cells expressing an empty vector in culture (PMID: 26884591).||26884591|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|