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Profile Name | FGFR2 - DDX21 |
Gene Variant Detail | |
Relevant Treatment Approaches |
Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|---|
FGFR2 - DDX21 | cholangiocarcinoma | sensitive | Debio 1347 | Case Reports/Case Series | Actionable | In a clinical case study, treatment with Debio 1347 resulted in stable disease for 5.5 months in a patient with cholangiocarcinoma harboring an FGFR2-DDX21 fusion (PMID: 34250419). | 34250419 | |
FGFR2 - DDX21 | cholangiocarcinoma | sensitive | Debio 1347 | Case Reports/Case Series | Actionable | In a Phase I trial, Debio 1347 treatment resulted in stable disease in a patient with cholangiocarcinoma harboring FGFR2-DDX21 (PMID: 30745300; NCT01948297). | 30745300 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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