Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ATM P960H||neuroblastoma||sensitive||PARP Inhibitor (Pan)||Olaparib||Preclinical - Cell culture||Actionable||In a preclinical study, Lynparza (olaparib) treatment of neuroblastoma cells in culture, transfected with Atm P960H, resulted in decreased cell viability as compared to cells carrying wild-type Atm (PMID: 29059438).||29059438|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|