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Profile Name | CSF1R W450_E456del |
Gene Variant Detail | |
Relevant Treatment Approaches |
Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|---|
CSF1R W450_E456del | Advanced Solid Tumor | sensitive | Pexidartinib | Preclinical - Cell culture | Actionable | In a preclinical study, transformed cells expressing CSF1R W450_E456del demonstrated sensitivity to treatment with Turalio (pexidartinib) in culture (PMID: 31768065). | 31768065 | |
CSF1R W450_E456del | Advanced Solid Tumor | sensitive | BLZ945 | Preclinical - Cell culture | Actionable | In a preclinical study, transformed cells expressing CSF1R W450_E456del demonstrated sensitivity to treatment with BLZ945 in culture (PMID: 31768065). | 31768065 |