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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|EML4 - ALK ALK G1202R ALK L1204V ALK G1269A||Advanced Solid Tumor||predicted - sensitive||TPX-0131||Preclinical - Cell culture||Actionable||In a preclinical study, TPX-0131 inhibited proliferation of transformed cells expressing ALK G1202R, ALK L1204V, and ALK G1269A compound mutation in the context of EML4-ALK in culture (AACR Virtual Annual Meeting II (Jun 2020), Abstract 52226).||detail...|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|