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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ATM T2333fs ATM neg||Her2-receptor negative breast cancer||predicted - sensitive||BAY1895344||Case Reports/Case Series||Actionable||In a Phase I trial, BAY1895344 treatment resulted in a partial response with a 54% decrease in tumor size in a patient with heavily treated, hormone receptor-positive, ERBB2 (HER2)-negative breast cancer harboring ATM T2333fs and ATM protein loss, who remained on treatment for 349 days (PMID: 32988960; NCT03188965).||32988960|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|