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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|KMT2A - AFF1 FLT3 exon 14 ins||acute myeloid leukemia||predicted - sensitive||CYC065||Preclinical - Cell culture||Actionable||In a preclinical study, an acute myeloid leukemia cell line harboring KMT2A-AFF1 and a FLT3-ITD was sensitive to treatment with CYC065 (Fadraciclib) in culture, demonstrating decreased cell viability (PMID: 32645016).||32645016|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|