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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|RET V804M RET G810S RET M918T||Advanced Solid Tumor||resistant||Selpercatinib||Preclinical - Cell culture||Actionable||In a preclinical study, transformed cells expressing RET V804M, G810S, and M918T were resistant to Retevmo (selpercatinib) treatment in culture (PMID: 33161056).||33161056|