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|Profile Name||PDGFRB A6V|
|Gene Variant Detail|
|Relevant Treatment Approaches|
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|PDGFRB A6V||colorectal cancer||predicted - sensitive||Regorafenib||Case Reports/Case Series||Actionable||In a clinical case study, a patient with metastatic colorectal cancer harboring germline PDGFRB A6V demonstrated a partial morphological and metabolic response after 8 weeks of treatment with Stivarga (regorafenib) and remained in partial remission with sustained clinical improvement for at least 9 months from the start of treatment (PMID: 25336117).||25336117|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|