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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FGFR2 - CCDC6 FGFR2 N549D FGFR2 N549K FGFR2 V564I||cholangiocarcinoma||predicted - resistant||Pemigatinib||Case Reports/Case Series||Actionable||In a Phase I trial (FIGHT-101), a cholangiocarcinoma patient harboring FGFR2-CCDC6 experienced disease progression after initially responding to Pemazyre (pemigatinib), and was found to have acquired FGFR2 N549K, FGFR2 N549D, and FGFR2 V564I (PMID: 35176457; NCT02393248).||35176457|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|