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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|BRAF mutant||Advanced Solid Tumor||predicted - sensitive||MLN2480||Preclinical - Cell culture||Actionable||In a preclinical study, MLN2480 inhibited downstream signaling and proliferation of several BRAF mutant solid tumor cell lines in culture (EJC Supp, Nov 2010, Vol 8(7), p40-41).||detail...|
|PubMed Id||Reference Title||Details|
|105 BIIB024, a potent pan-Raf kinase inhibitor for melanoma and solid tumors||Full reference...|