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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||renal cell carcinoma||no benefit||Axitinib + Dalantercept||Phase II||Actionable||In a Phase II trial (DART), the combination of Dalantercept (ACE-041) and Inlyta (axitinib) did not significantly improve median progression-free survival (6.8 vs 5.6 months, HR=1.11, p=0.670), median overall survival (HR=1.39, p=0.349), or objective response rate (11/38, 19.0% vs 15/61, 24.6%) compared to placebo plus Inlyta (axitinib) in patients with advanced renal cell carcinoma (PMID: 30951193; NCT01727336).||30951193|