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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ETV6 - SYK||Advanced Solid Tumor||sensitive||HMPL-523||Preclinical - Cell culture||Actionable||In a preclinical study, HMPL-523 decreased viability of cells expressing ETV6-SYK in culture (Blood Dec 2016, 128 (22) 3970).||detail...|
|PubMed Id||Reference Title||Details|
|HMPL-523, a Novel SYK Inhibitor Showed Anti-Tumor Activities In Vitro and In Vivo||Full reference...|