Profile Response Detail

Molecular Profile MET positive
Therapy ARGX-111
Indication/Tumor Type Advanced Solid Tumor
Response Type sensitive
Create By cstatz
Update By cstatz


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
MET positive Advanced Solid Tumor sensitive ARGX-111 Phase I Actionable In a Phase I trial, ARGX-111 demonstrated safety and resulted in some efficacy in patients with advanced solid tumors expressing MET, including a decrease in circulating tumor cells positive for MET (Journal of Clinical Oncology 33, no. 15_suppl, May 2015, 2580-2580). detail...
PubMed Id Reference Title Details
A phase I, first-in-human study of argx-111, a monoclonal antibody targeting c-met in patients with solid tumors Full reference...