Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FGFR3 S249C||urinary system cancer||sensitive||AZD4547||Preclinical - Cell line xenograft||Actionable||In a preclinical study, AZD4547 decreased Myc expression and inhibited growth of a urinary tract cancer cell line harboring FGFR3 S249C in culture and in xenograft models (PMID: 27401245).||27401245|