Profile Response Detail

Molecular Profile Unknown unknown
Therapy Quisinostat
Indication/Tumor Type colon cancer
Response Type not applicable
Create By spatt
Update By spatt


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colon cancer not applicable Quisinostat Preclinical - Cell line xenograft Actionable In a preclinical study, Quisinostat (JNJ-26481585) induced apoptosis and inhibited proliferation of colon cancer cell lines in culture, and inhibited tumor growth in a colon cancer cell line xenograft model (PMID: 19861438). 19861438
PubMed Id Reference Title Details
(19861438) JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity. Full reference...