Molecular Profile | Unknown unknown |
Therapy | CVX-060 + Sunitinib |
Indication/Tumor Type | colon cancer |
Response Type | not applicable |
Create By | spatt |
Update By | spatt |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References | Unknown unknown | colon cancer | not applicable | CVX-060 + Sunitinib | Preclinical - Cell line xenograft | Actionable | In a preclinical study, treatment with the combination of CVX-060 and Sutent (suntinib) resulted in increased tumor growth inhibition compared to either agent alone in a colon cancer cell line xenograft model (PMID: 21233403). | 21233403 |
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PubMed Id | Reference Title | Details |
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(21233403) | Specifically targeting angiopoietin-2 inhibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth. | Full reference... |