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Molecular Profile Unknown unknown
Therapy Pembrolizumab
Indication/Tumor Type transitional cell carcinoma
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown transitional cell carcinoma not applicable Pembrolizumab FDA approved Actionable In a Phase III (KEYNOTE-045) trial that supported FDA approval, treatment with Keytruda (pembrolizumab) resulted in improved median overall survival (10.3 vs 7.4 months, p=0.002) and objective response rate (21.1% vs 11.4%) compared to chemotherapy in patients with platinum-refractory advanced urothelial carcinoma (PMID: 28212060; NCT02256436). detail... 28212060
PubMed Id Reference Title Details
(28212060) Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma. Full reference...
Keytruda (pembrolizumab) FDA Drug Label Full reference...