Profile Response Detail

Molecular Profile Unknown unknown
Therapy E7046 + Radiotherapy
Indication/Tumor Type colon cancer
Response Type not applicable
Create By cstatz
Update By cstatz


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colon cancer not applicable E7046 + Radiotherapy Preclinical Actionable In a preclinical study, the combination treatment of E7046 and radiotherapy resulted in 9 out of 12 tumor free colon cancer mouse models and increased the number of T-cells infiltrating the tumor (International Journal of Rad Onc, 2016, 96;2, S128). detail...
PubMed Id Reference Title Details
Combination of a Novel EP4 Antagonist E7046 and Radiation Therapy Promotes Anti-tumor Immune Response and Tumor Rejection in Preclinical Tumor Models Full reference...