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Molecular Profile Unknown unknown
Therapy SY-1365
Indication/Tumor Type triple-receptor negative breast cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown triple-receptor negative breast cancer not applicable SY-1365 Preclinical - Pdx & cell culture Actionable In a preclinical study, SY-1365 induced rapid apoptosis in triple-receptor negative breast cancer cells in culture, and resulted in tumor growth inhibition in patient-derived xenograft models (Proceedings of the AACR, Vol 58, April 2017, Abstract # 1151). detail...
PubMed Id Reference Title Details
SY-1365, a potent and selective CDK7 inhibitor, exhibits promising anti-tumor activity in multiple preclinical models of aggressive solid tumors Full reference...