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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||Advanced Solid Tumor||not applicable||ETC-159||Phase I||Actionable||In a Phase I trial, treatment with ETC-159 was well-tolerated, decreased Wnt signaling, and resulted in stable disease in 2 out of 16 treated patients with advanced solid tumors (J Clin Oncol 35, 2017 (suppl; abstr 2584)).||detail...|
|PubMed Id||Reference Title||Details|
|First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours||Full reference...|