Profile Response Detail

Molecular Profile Unknown unknown
Therapy ETC-159
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable
Create By spatt
Update By spatt


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable ETC-159 Phase I Actionable In a Phase I trial, treatment with ETC-159 was well-tolerated, decreased Wnt signaling, and resulted in stable disease in 2 out of 16 treated patients with advanced solid tumors (J Clin Oncol 35, 2017 (suppl; abstr 2584)). detail...
PubMed Id Reference Title Details
First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours Full reference...